MORE COMPLEX INFLAMMATORY RESPONSES, INFLAMMATORY DISEASES AND NEW PROSPECTS FOR THERAPY

While (Pneumonia) streptococcal pneumonia exemplifies and acute inflammatory response in which the recruited cells are virtually restricted to neutrophil granulocytes and cells of the monocyte/macrophage lineage, in other situation, e.g. some viral infections, large numbers of lymphocytes are recruited. This more persistent tissue picture results from a combination of the inflammatory and classical immune responses. (Health Education) Read more…

The acute inflammatory Response

The acute inflammatory Response

In a classical acute anti-inflammatory response, such as occurs as a result of streptococcal invasion of the lung airspaces in the evolution of labor streptococcal pneumonia , a stereotyped sequence of cellular and mediator events is usually provoked (see fig. 1.22): (Health Education) Read more…

The Eosinophil Granulocyte

Like the neutrophil, the eosinophil is a bone ma

The Eosinophil Granulocyte

rrow derived, blood-borne polymorphonuclear leucocyte, but unlike the neutrophil its cytoplasm stains pink on haemotoxylin/eosin staining, and electron microscopy (see fig: 1.21) (Health Education) Read more…

The Macrophages

The Macrophages

Resident tissue macrophages, e.g. Kupffer cells in the liver, alveolar macrophages in the lung, mesangial cells in the kidney, microglial cells in the brain and resident macrophages in the peritoneum and lymph nodes, derive from circulating monocytes which originate in the bone marrow. Tissue macrophages have a number of important functions (see the information box) (Health Education) Read more…

The neutrophil granulocyte

Neutrophil Granulocyte

Neutrophils are short-lived, bone marrow-derived (half-life 6 hours), circulating white blood cells with a diameter of about 5.5 µM. on ultrastructure (see fig: 1.20) they contain a large number of cytoplasmic granules, which in turn contain a large number of powerful agents (see table 1.2), (Health Education) Read more…